I don't want to give away too much, as game planning is hard enough against the good managers, but...
Don't just trust the run/pass ratio the defense page gives you. Think in terms of how a game goes, and how good the team is. Are they getting all those runs at the end of the game, when they're protecting a lead?
Look at a couple of their previous games in the play by play, especially games against you, or at least teams similar in strength to yours. Look for patterns like, "mostly passes on 1st down on their own side of the field", or things like that.
(I feel like I gave away too much.)